Abstract Hypoxia, characterized by reduced oxygen concentration, is a significant stressor that affects the survival of aerobic species and plays a prominent role in cardiovascular diseases.From the research history and milestone events related to hypoxia in cardiovascular development and diseases, The "hypoxia-inducible factors (HIFs) switch" can
The KINETIC phase 2 randomized controlled trial of oral pamapimod-pioglitazone in non-critically ill COVID-19 inpatients
Summary: The combination of pamapimod and pioglitazone (KIN001) has a synergetic antiviral, anti-inflammatory, and antifibrotic activity, 1073spx which may prevent evolution toward COVID-19-associated severe respiratory failure.In a randomized, placebo-controlled, double-blind, phase 2, multicenter trial, 128 non-critically ill hospitalized patient
Justification for choosing the optimal technology for controlling the transportation operation of locomotives
The choice of some elements of the material and technical base and the organization of work under the conditions cga 200 to cga 510 adapter for optimizing the transportation work of locomotives is analyzed.The criterion for this choice is the gain parameter in the form of annual reduced economic and operating costs, determined on the basis of tract
Systemic analysis of production scenarios for bioethanol produced from ligno-cellulosic biomass [abstract]
Defining alternatives for non-renewable energy sources constitutes a priority to the development of our societies.One of these alternatives is biofuels production starting from energy crops, agricultural wastes, forest products or wastes.In this context, a "second generation" biofuels production, revlon colorstay lip liner plum aiming at utilizing